The Keedy Lab


End of summer 2020 update

Daniel Keedy
22 September 2020

It’s been a while since the last post! (I have a feeling this won’t be the last time that happens…) Let’s attempt to fill in some gaps in the timeline:

Since my last post, the COVID-19 pandemic hit. Our wet lab was shut down for months, and we shifted toward data analysis, planning future experiments, and computational projects. Thankfully we’re now back in action in a careful, socially distanced mode. Despite the challenges of the moment, we’ve managed to see each other in person from time to time:

One of those occasions was when Maryam finished her >2 year tenure with us! :cry: (See photo below – including social-distancing-friendly elbow bumps.) But she’s going on to bigger and better things with the CUNY Molecular, Cellular, and Developmental Biology (MCD) PhD Program. We’ll miss you, Maryam – but at least you won’t be too far away!

On the flip side, we’ve had some fantastic new additions to the lab. First up: Virgil Woods, a new PhD student from the CUNY Biochemistry PhD Program. Second: Yingxian Tan, an undergraduate student from The City College of New York. You can read more about both over on our Members page. Welcome, Virgil and Yingxian!

We are also very excited to begin working with Dr. Ali Ebrahim, currently at Diamond Light Source, on some avant-garde new crystallographic experiments – more to come on our projects together quite soon…

On the science side: in October, Daniel gave a “virtual” talk on our (ongoing!) efforts to develop allosteric small-molecule modulators of PTP1B at the American Chemical Society national meeting. Thanks to our collaborators at Atomwise, you can view it here.

Finally, the lab has published its first multi-author paper on which Daniel is a corresponding author, initially as a bioRxiv preprint but with a peer-reviewed journal article to come soon. Blake did an admirable job shaping this up and getting it out to the world. Check out qFit 3 on GitHub and try it yourself!

We have several other interesting stories cooking right now – so stay tuned for more in the not-too-distant future…

Tamar passes her qualifying exam

Daniel Keedy
14 August 2019

Tamar Skaist passed her second level exam (i.e. qualifying exam) today – the day before her birthday, by the way. Double celebration! Congrats, PhD candidate Tamar!

Happy birthday AND congrats on passing, Tamar!

End of summer 2019 update

Daniel Keedy
08 August 2019

A lot has happened in the Keedy Lab in the last few months…

First of all, I’m excited to report that the lab has been awarded an NIH MIRA (R35) grant, which will provide funding for 5 years! With this support from the NIH, we can continue our work to develop new methods in multistate X-ray crystallography and elucidate allosteric mechanisms in phosphatases.

Relatedly, we are hiring for multiple positions in the lab. Email Dr. Keedy and apply by clicking this link if you are interested in a postdoc position.

Finally, two excellent undergraduates have finished their summer research in the lab: Kristiana “Spring” Smith with the B^3 REU Program (from my alma mater Rhodes College!) and Minyoung “Lily” Kim with the CSURP Program, both of whom worked with Maryam Azeem as a mentor here. We wish them both the best as they return to college for the fall, and beyond!

DK, Spring Smith, and Maryam Azeem in August 2019

DK, Lily Kim, and Maryam Azeem in August 2019

Welcome to the Keedy Lab website!

Daniel Keedy
02 June 2019

Hello, world! This is the first post from the Keedy Lab. Only 1+ year late!

We’ve gotten off to an amazing start in that time. See below for a photo of the lab during the 2018 holiday season.

Looking forward to what the rest of 2019 and beyond have to bring! Watch this space…

Finally, if you are interested in a postdoc position in the lab, please apply by clicking this link.

… and email Dr. Keedy to discuss!

the Keedy Lab in December 2018